Genetics of neurodegenerative diseases

Dr. Shubhabrata (Joey) Mukherjee, research associate professor (General Internal Medicine) is principal investigator together with Dr. David Fardo (University of Kentucky) on a $5.08 million R01 from the National Institute on Aging for the project “Genetic architecture of pure Alzheimer’s disease and mixed pathology.”

The study aims to elucidate the genetic factors explaining why some people develop Alzheimer’s type neuropathology alone while others develop Alzheimer’s type neuropathology together with other forms of neuropathology.

The project includes collaborations with colleagues from the University of Wisconsin, the Allen Brain Institute, and the University of Kentucky.

Dr. Mukherjee is trained in statistics, psychometrics and genetics related to Alzheimer's disease research. He has been the lead genetic analyst for the Adult Changes in Thought (ACT) study and active member of the Alzheimer's Disease Genetics Consortium.