This is unpublished
July 28, 2023
RNA stability may play a role in prostate cancer
New research links mutations in RNA region that helps regulate protein production to progression and drug resistance
Scroll for more
Mutations in a genetic region that regulates RNA stability could influence prostate cancer outcomes and drug resistance, according to new work from scientists at Fred Hutchinson Cancer Center published today in Cell Reports.
“The basic takeaway is that the lifecycle of an RNA [molecule] is really important for prostate cancer — and it’s functionally associated with patient outcomes,” said Fred Hutch prostate cancer expert Andrew Hsieh, MD, the study’s senior author.
The team developed innovative new techniques to test whether cancer-associated mutations in a little-studied and still mysterious region of RNA could affect protein production and cellular function.